Is There a Test for Degenerative Myelopathy For My Dog?

Yes, there is a test for Degenerative Myelopathy for your dog! 

There’s no definitive test for Degenerative Myelopathy (DM). It can only be positively diagnosed post mortem.

However, through genetic testing, it’s possible to eliminate DM as a potential cause of rear leg weakness or paralysis (i.e. it can be ruled out definitively, but it can’t be confirmed definitively while a dog is still alive).

SOD1 is the gene in question. It produces an enzyme called Superoxide Dismutase which helps protect cells against the damage caused by free radicals. Mutations in this gene are linked to DM because the enzyme doesn’t function properly, therefore the cells don’t have their usual protection against degeneration.

It’s not the only gene that’s indicated in the development of DM, but its presence or absence gives a strong clue as to whether or not a dog has DM.

Testing is done, with help from your vet, via a blood sample or saliva test kit that can be sent off.

NO SOD1 gene mutations - normal / clear - it is extremely unlikely that DM will develop

1 copy of SOD1 gene mutation - not likely that DM will develop 

2 copies of SOD1 gene mutation - at risk / affected - DM could possibly develop

It is advisable to have this gene test done if you are considering breeding, as it will help make informed breeding decisions. It can also be used as information to help build up a picture of a dog if there’s suspicion that certain symptoms are caused by DM. However, this test cannot confirm a diagnosis of DM.

Read more about Degenerative Myelopathy here

Read more about Degenerative Myelopathy - Causes, Prevention and How To Help https://zoomadog.co.uk/collections/degenerative-myelopathy

Read more about dog wheelchairs here

Read how a dog wheelchair can help your dog live an active life with Degenerative Myelopathy https://zoomadog.co.uk/collections/dog-wheelchairs